In the near future, I want to use macrium to clone the image, how will I do that if it won't boot from usb?
I wouldn't worry about that yet. You need to figure out WHY this is happening instead of worrying about things you can't do yet.
Okay, lets back up a step here. Probably a stupid question, but have you tried using a different USB drive in the event the first one is defective? Flash drives, no matter where you get them or who makes them, are all cheaply made crap subject to failing at the drop of a hat.
If you have tried a different USB drive and it still won't work, DO THE DIAGNOSTICS!
A bad memory module or a failing hard drive can cause these types of problems. So could a failing power supply or even a hardware fault on the motherboard (i.e. not providing sufficient voltage to the USB ports).
Try to check the things you can easily check first. If you find something you can fix, like a bad memory module or a failing hard drive, you fix it and the problem may go away.
If the diagnostics don't show anything, it could be a motherboard fault. In that case, if you want to take a chance, you can purchase a cheapo USB3.0 PCIe card off Amazon or eBay to see if you can use that to boot and/or image the computer.