Look at the P4X400 when it comes out. It will have a updated southbridge and the newwer north bridge.
I have always run VIA chipsets and if you use a OS other then Win XP you will have to install the 4in1's and maybe some patchs, but that was because Windows was in bed with Intel. Now that microsoft supports VIA it even easier to setup a VIA board.
I have used just about every VIA chipset from MVP all the way to KT266a. I am waiting for the KT400 now, but for intel people wait for the P4X400