Because different alcohols (beer, wine, liquor, etc.) have different congeners, the various impurities can combine in less-than-pleasant ways, revealing the truth behind some popular reminders: "Don't mix the grape and the grain" (don't mix wine with liquor or beer) and "Beer before liquor, never been sicker. Liquor before beer, have no fear." The latter of the two also stems from the fact that the carbonation in beer actually speeds up the absorption of alcohol; therefore, following it with liquor gives the body even less time than usual to process the toxins -- often leading to a close encounter with "the porcelain god."