Asus makes motherboards (for the most part) for AMD and Intel. Did you mean AMD vs Intel ? And what are the requirements ? What parts are required ? I display or not ? Most likely at $300 you will be restricted by price more than anything, and since in general at the low end, AMD is a better value, you will probably end up in that direction, however for a business box in general, A dell may be the only way to go, at least a possibility.