Long time lurker here.
I ordered one of these from NCIX last week and installed it a few days ago in a new system. So far it's been rock-solid for me running F@H for 72 hours straight while simultaneously formatting 1tb of hard drive space. In fact it's the only build I've done that's been completely problem free from assembly through XP install, although that probably says more about me than the board. I've tweaked it a little at this point, waiting until after the holiday to really push it when I have some free time. The BIOS is very straightforward, which is good, because the ASUS utilities (first ASUS board) in the OS are visually maddening from my point of view.
I'm using 2gb Corsair XMS2 DDR800, two Seagate 7xxxx.10 (I think?, whatever the perpendicular read models are, interesting noises on these, but not loud) 500mb HDs, C2D 6600, Evga 8800 GTS, PCP&C silencer 750, and stock cooling in a p180 until my tuniq arrives hopefully today.