I've been using one for a few months now under WinXP SP2, an E6300, DDR2 ram and an AGP 9800 Pro. Overclocking isn't so great.
Something's horribly wrong with my USB drivers that I've never been able to figure out. While USB storage devices show up, their data can not be seen. Clicking on a device (USB mediacard reader's SD and microSD slots, tons of different flash drives, a Western Digital external 500gb, etc) comes back with "Would you like to format this device" even though they all work fine on any other computer. I'm getting ready to upgrade to a P3K or P5B and maybe use this in a sub-system.