<< I assume it was the 'self administered antibiotics' that made you think this might be a total 'do-it-yourself' project. >>
I had a mental image of someone trying to insert this themselves. hehe
<< Would a central line catheter be ran from the upper thigh to the SVC, or are all central lines inserted from the upper arm, chest area or jugular? >>
There are three main central venous access sites; subclavian, internal jugular, and femoral. They all use a catheter of required length to reach the SVC. Wow, I've seen a hundred of them, but I left the medical field three years ago and its all becoming a blur now. I guess if you don't use it, you lose it.
A PICC line is the same thing, except it is typically a smaller diameter tube and is inserted into a large vein in the arm (cubital, cephalic, etc.). The delivery port is usually just like an IV piggy-back port, not an implant.