A good friend of mine is schizoaffective. I'm still not completely sure how that's defined but in his case, he will sometimes imagine that people know what he's thinking and are passing judgement on him. That's just one example though. I have no personal experience with the type conceived of in the public imagination - IOW (in other words) "reality" serves no purpose for them except the wardrobe's gateway to Narnia.
That said, my friend does have a very low tolerance for certain seemingly innocuous and anodyne things like movies. I'm not his shrink and would never try to be, so the link isn't very clear to me but I accept him for the nutball he is and vice-versa - or so I assume.
What I will say though, and you'll have to do some research to make sure that I'm not inadvertently "lying" to you, is that many (probably most) mental illnesses can, as presented by individual sufferers, have apparently irrelevant things "trigger" the re-emergence of the disease.
As long as he's on his meds, he's just a normal guy. The triggers are still triggers, but the drugs give him the power to put them in their unwelcome place.
However for someone who falls within the very fat one standard deviation from the mean of the bell curve that we consider "normal," I think if it affects anyone at all, it will be along the lines of those animes that were shown to induce seizures in sensitive people. If you're not familiar with this episode in anime history and lore, the fast, stroboscopic changing of scenes, perspective, colors etc. seems to have been overwhelming for them.