I have issues with a front weight loaded headwear over time - even wearing a headphone headset can be wearing over the course of computer usage. This offsets that benefit one has for potentially offering "infinite space" by simply moving your head around, versus a multi monitor setup surrounding in a semi circle. Even if the whole weight is distributed, it is going to be as comfortable as wearing a motorcycle helmet when using a computer.
The other issue, is the amount of energy outputted to your eyes at a close proximity. Even if it is at a low wattage, it is basically looking at a light bulb at a very close distance, and with the square inverse law, it is beneficial from an eye strain standpoint to still use monitors at a good viewing distance, in a balanced lighted room in accordance to the screen for working over time.
One would still need monitors for screen sharing with others for local collaboration, and the other audience members simply cannot point out where they need to direct the Occulus Rift wearer's attention as easily unless the audience has vocabulary descriptions matching the comprehension and understanding of the VR wearer.
The ONLY benefit, is to eliminate periphery view from the wearer, in fully taking in the entire vision view, but my eyes and peripheral input devices (at most two hands) are already directed at the focal point of work, any periphery - is simply luxury viewing experiences - and even then, my attention would be directed at one area dominantly.
