Once again thanks for bringing up this great deal. Picked up a copy of Vista Ultimate Upgrade for $155.99+tax and I'll be adding the 2 Home Premiums from the MS site.
They had a lot of other versions also: Upgrades for Home Basic, Premium, Office, and Ultimate. Full versions of Home Basic, Premium, and Office. The Upgrade prices for Home Basic and Premium were really compelling....$59.99+tax for Basic and $83.99+tax for Premium.
I only really need Home Premium but neither the Full or Upgrade versions they had include the 64-bit disc, so I didn't want to deal with getting that from MS (probably costs another $20) and I wanted to get the 2 extra keys anyways. I'm pretty sure you can get Home Premium versions with the 64-bit install disc, they just didn't have any.
They also had "Service Desk" versions which were the same as the Upgrade versions as far as I could tell, just with a smaller box. If your CompUSA only has these left I'd make sure they're the same as the retail and not the OEM. I think there's some difference in how many times you can re-ctivate the retail vs. OEM keys but I'm not 100% sure on that.