- Nov 30, 2005
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On ingestion, absorption is delayed due to the low pH in the stomach, leading to a maximum concentration in the blood after 45 to 90 minutes.
After insufflation (the medical term for 'snorting'), the maximum concentration in the blood (well, plasma, actually) is reached after about 30 to 120 minutes, although mostly on the lower time scale.
(Why the hell would you insufflate it if it were the other way around? Because it looks cool?). Admittedly, ingesting a larger amount of coke would probably lead to an earlier plasma peak because of constriction of the blood vessels in the nasal mucosa (the inner lining of the nose) limiting absorption into the bloodstream
Effects: hypertension (high blood pressure), tachycardia (high heart rate), constriction of the blood vessels around the heart (myocardium), all sorts of muscle effects (spasms, tremors, rigidity) >> brain haemmorhage, myocardial infarction are early effects (cocnurrently with tachycardia eand hypertension, in later phases come rhadbomyolysis (muscle tissue breakdown) and renal insufficiency. Shitty way to die.
And for what it's worth: 1 gram of cocaine is enough to kill an inexperienced user; 5 grams is regularly fatal for even the most hardened ones. Here in Holland, it is rumored it was 450 grams (insane amount), in the US news outlets, it's gone dowen to an ounce, which is about 28 grams if I'm not mistaken. Still very much deadly. The only thing saving most users is the fact that they get very impure cocaine --- one of the few instanced in which being frauded actually saves your life.
(I'm an information specialist in a poison control center in Europe, so this is my job.)
Nice first post! :thumbsup:
KT