I had to send my XSi back after a couple months due to an excessive number of hot pixels, several grouped together creating giant red blobs on my images. The first repair attempt left me with serious banding issues, and still a rather large number of hot pixels (though not as concentrated or bad as before), and after a week or so of using it, decided to send it back again. Whatever they did the second time different than the first worked great, and I couldn't be happier with my XSi now. Not having it for a couple of months though was really frustrating.
The leaked Nikon roadmap in the thread JP linked is interesting; I've been planning to upgrade to a full-frame camera by the end of this year/early next year, and between the potential D700 replacement from Nikon, and Canon's seemingly increasingly poor quality, I'm considering switching. Luckily I don't have that much invested in EF lenses, and was planning to buy a couple with the 5D2, so if I do switch to Nikon I won't technically lose *too* much.
I still have some time to think it out, and make sure the Nikon roadmap is real, and consider whether I really do want to give up on Canon; but once I have more than $1200 into either brand, I think that's where I'll be staying for awhile.