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Xanathar,
This is a VERY big Yes, i have seen it done with an AT keyboard and a 386, the keyboard had a short in it and sent feedback along a live wire and fried the mobo.
think copper smelling smoke 
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Someone in my Freshman dorm did that once, the moron desided to try cleaning his keyboard(removing keys, etc.etc.) while still running....Can you say burning Mobo?
CAn't think of many, but.....
Easy - Whats POSIX?
WIndows NT is based off of what form of Unix?
Why is Cisco equipment a pain to configure? (our cabletron stuff was Simple)
Port Trunking, what is it?
Name the .dll that has to be disabled/renamed when setting up a Novell/2k client machine with a G2xx-G4XX matrox card.
Name the company that help Microsoft with the NT kernel
The command line for pulling a ZenWorks image from a server is?
The longest uptime for a Novell server is?