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You always hear about people getting money from drug trials...

T

TheCanuck

Senior member
ELEPHANT MEN
EXCLUSIVE Anguish of families as drugs trial volunteers lie critically ill after the experiment goes wrong
Drug Trial Goes Wrong

God that would suck...there you are thinking you'll make an easy $2000 and your head practially explodes!
 
Folks, this is why we have the concept of informed consent when participating in clinical drug trials.
 
Originally posted by: Mwilding
Folks, this is why we have the concept of informed consent when participating in clinical drug trials.
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true. they most likely signed off.

also, this is another reason to run trials on animals.

 
right...i'll believe that when i see it with my own two eyes, not a photoshopped image. anyway, they always try these drugs out on animals first and i seriously doubt that this is real. like JoePa said, did u look at the source?
 
Originally posted by: ForumMaster
right...i'll believe that when i see it with my own two eyes, not a photoshopped image. anyway, they always try these drugs out on animals first and i seriously doubt that this is real. like JoePa said, did u look at the source?
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did you read my post?

 
I guess there's no such thing as a free lunch. But I'm surprised that they didn't at least anticipate this could happen...when it happened to everyone that took it.
 
Originally posted by: moshquerade
Originally posted by: Mwilding
Folks, this is why we have the concept of informed consent when participating in clinical drug trials.
Click to expand...
true. they most likely signed off.

also, this is another reason to run trials on animals.
Click to expand...

Phase I human trials are not initiated until sufficient data exists from in situ and animal trials to SUGGEST that it will be safe in humans. Unfortunately, there is no real way of knowing until you give it to a human...
 
Originally posted by: moshquerade
Originally posted by: JoePa
Did you look at the source?
Click to expand...
scores of other sources are reporting the same story.
google news search
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wow mosh, u're right. there was a delay from when i clicked the link till i saw ur post. i take what i said back, and agree with u. why didn't they first try it out on animals? not that i'm a big fan of animal trials, but something like this does make u reconsider.
 
Can't these crazy doctors just inject these experimental and untested drugs into themselves first, like the green goblin from spiderman. I thought that was how it worked.
 
Originally posted by: PingSpike
Can't these crazy doctors just inject these experimental and untested drugs into themselves first, like the green goblin from spiderman. I thought that was how it worked.
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i love those movies. when is the next one due out?
 
I've done a few, and the only problem I have is that some of the drugs side effects are minimized by the people administering them to you, so that you don't decide not to do the trial. Also, they really don't pay enough for the service you are doing them, considering that if the drug makes it to market, they stand to make many millions on it. Some of the trials I have done paid less than $500, and turned out to have some pretty crappy side effects, such as inability to get or sustain and erection, explosive diarreah, etc. $500 is not enough if it blows my rectum out while I struggle to keep an erection.
 
There is a hell of a lot of testing that you have to do before you even consider trying it in a human. I work at a company that makes medical equipment, and even just an upgraded device needs to go through alot of validation and verification before being used in an animal study. And our stuff isn't nearly as critical as a drug would be. I'm sure if there was a way that what happened could have been prevented, they would have done it.
 
It sounds like it is time for remedial drug testing and approval...

Here is a typical pathway from discovery to market for a drug:

1. A drug company develops a compound in the lab that they think might be able to be used to treat a disease.
2. The drug company does "petri dish" tests to see if it has an effect on the desired cellular biochemical pathways.
3. The drug company sees that this drug has promise as a novel treatment and continues testing.
4. The drug company does a series of tests in animal systems to study the drug. Multiple studies are conducted to test safety, toxicity and efficacy.
5. The drug company sees that this drug has promise as a novel treatment and continues testing.
6. The drug company gives the drug to a small number of healthy volunteers in a controlled environment. The main purpose of these tests is safety. Things like how long the body takes to metabolize the drug are also measured.
7. If the drug proves to have an acceptable safety profile (allergy meds have to be REALLY safe, cancer drugs not so safe), the drug company will conclude that this drug still has promise as a novel treatment and will continue testing.
8. The drug company begins Phase II and tests the drug in a small group of people with the target illness. Safety, efficacy are closely watched. They also try to identify the best dosage for therapeutic effect.
9. The drug company sees that this drug has promise as a novel treatment and continues testing.
10. Phase III starts - the drug company has physicians treat a large number of patients in a real world setting and huge amounts of safety and efficacy data is collected.
11. The drug company sees that this drug has promise as a novel treatment and continues on towards getting approval.
12. The drug company fills several 18 wheelers with data from all of the trials and submits it to the FDA.
13. The FDA scrutinizes the data and if necessary directs the company to do further tests.
14. The FDA approves / rejects the drug.

This process takes many years and many millions of dollars.
 
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