Xyzal allergy medicine

moshquerade

No Lifer
Nov 1, 2001
61,504
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I think it was just FDA approved to be prescribed in the U.S. a couple of months ago. It's pretty much like Zyrtec, which went OTC about the time Xyzal came out.

Anyone on Xyzal or know anyone who is? If so, opinions on it would be appreciated.
 

Darkstar757

Diamond Member
Feb 1, 2003
3,190
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I recommend sublingual drops. This is what I am taking to get rid of my allergies.


Darkstar
 

moshquerade

No Lifer
Nov 1, 2001
61,504
12
56
Originally posted by: Darkstar757
I recommend sublingual drops. This is what I am taking to get rid of my allergies.


Darkstar

sublingual drops of what? Xyzal?
 

Darkstar757

Diamond Member
Feb 1, 2003
3,190
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They are FDA approved but they are not covered by insurance I pay 180 for three months.

 

PlasmaBomb

Lifer
Nov 19, 2004
11,636
2
81
Zyrtec is Cetirizine Hydrochloride
Xyzal is Levocetirizine Hydrochloride

Zyrtec is a racemic mix of the two chiral forms of Cetirizine
Xyzal is a singal enantiomer of cetirizine.

Whats the difference? Typically one enantiomer will have a much higher activity than the other due to receptor binding. So you can give a lower dose (Zyrtec is 10 mg Xyzal is 5 mg), with the same or greater efficacy (since the less active form doesn't interfere) and less side effects.

So why aren't all drugs sold as single enantiomers? There is currently a shift to this, but the main reasons are cost and licensing. If you can only manufacture a racemic mix splitting the two very similar components can be difficult = large cost. If you have to redesign the synthesis to produce a single enantiomer = large cost. If you bring out a single enantiomer of an existing drug it has to go through FDA/regulatory approval = time and money.

Any other questions feel free to ask :)
 

Darkstar757

Diamond Member
Feb 1, 2003
3,190
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81
But I am very allergic and have a higher dose than most. So most folks is 90 for three months.
 

PlasmaBomb

Lifer
Nov 19, 2004
11,636
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81
Originally posted by: Darkstar757
They are FDA approved but they are not covered by insurance I pay 180 for three months.

The linky says that they aren't FDA approved yet.
 

PlasmaBomb

Lifer
Nov 19, 2004
11,636
2
81
If they are as good as the injections* they should have something like a 95% success rate :D

(* which the website claims)
 

Darkstar757

Diamond Member
Feb 1, 2003
3,190
6
81
Originally posted by: PlasmaBomb
Originally posted by: Darkstar757
They are FDA approved but they are not covered by insurance I pay 180 for three months.

The linky says that they aren't FDA approved yet.

my Dr told me they are just about done its just the FDA dragging its feet cause the insurance companies dont want to have to pay.
 

PlasmaBomb

Lifer
Nov 19, 2004
11,636
2
81
Originally posted by: Darkstar757
Originally posted by: PlasmaBomb
Originally posted by: Darkstar757
They are FDA approved but they are not covered by insurance I pay 180 for three months.

The linky says that they aren't FDA approved yet.

my Dr told me they are just about done its just the FDA dragging its feet cause the insurance companies dont want to have to pay.

LOL... I don't think that the FDA care about the insurance companies, they are just generally slow.

Originally posted by: George P Burdell
How does it fare when compared to Zyrtec?

Sorry what do you want compared to zyrtec? Xyzal is better, immunotherapy (the drops/injections) is better in the long term, as it can actually cure you, however there are more risks, so you need to deal with someone who knows what they are doing.
 

imported_Lothar

Diamond Member
Aug 10, 2006
4,559
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Originally posted by: George P Burdell
How does it fare when compared to Zyrtec?

Xycal isn't any better than Zyrtec.
There is no statistical significance.

Just take the one that's cheaper per pill.
 

imported_Lothar

Diamond Member
Aug 10, 2006
4,559
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And FYI, Xyzal 2.5mg is equivalent to Zyrtec 5mg.

30 day supply of Zyrtec 5mg is cheaper than Xyzal 2.5mg where I work at.
The same is true when comparing Zyrtec 10mg with Xyzal 5mg as well.
 

moshquerade

No Lifer
Nov 1, 2001
61,504
12
56
Originally posted by: Lothar
And FYI, Xyzal 2.5mg is equivalent to Zyrtec 5mg.

30 day supply of Zyrtec 5mg is cheaper than Xyzal 2.5mg where I work at.
The same is true when comparing Zyrtec 10mg with Xyzal 5mg as well.

Yes but Zyrtec is OTC, and Xyzal isn't. So if you have good RX insurance Xyzal could come up cheaper than Zyrtec.

Still no one taking Xyzal here?
 

imported_Lothar

Diamond Member
Aug 10, 2006
4,559
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Originally posted by: moshquerade
Originally posted by: Lothar
And FYI, Xyzal 2.5mg is equivalent to Zyrtec 5mg.

30 day supply of Zyrtec 5mg is cheaper than Xyzal 2.5mg where I work at.
The same is true when comparing Zyrtec 10mg with Xyzal 5mg as well.

Yes but Zyrtec is OTC, and Xyzal isn't. So if you have good RX insurance Xyzal could come up cheaper than Zyrtec.

Still no one taking Xyzal here?

Depends...

Some insurance *may* still cover Zyrtec.
The same reason why some insurance still cover encoated aspirin, Prilosec, and Doc-Q-Lace(Colace).
Have the person call their insurance to find out.

You can also look into getting store brand products of Zyrtec. Same amount of active ingredients really.
Walgreens brand, Rite-Aid brand, etc...It may even end up costing less than Xyzal with insurance.
I doubt most insurance will charge less than $20 for 30 tabs of Xyzal (unless the person is on Medicare/medicaid)
Most likely $20-30.
 

moshquerade

No Lifer
Nov 1, 2001
61,504
12
56
Originally posted by: Lothar
Originally posted by: moshquerade
Originally posted by: Lothar
And FYI, Xyzal 2.5mg is equivalent to Zyrtec 5mg.

30 day supply of Zyrtec 5mg is cheaper than Xyzal 2.5mg where I work at.
The same is true when comparing Zyrtec 10mg with Xyzal 5mg as well.

Yes but Zyrtec is OTC, and Xyzal isn't. So if you have good RX insurance Xyzal could come up cheaper than Zyrtec.

Still no one taking Xyzal here?

Depends...

Some insurance *may* still cover Zyrtec.
The same reason why some insurance still cover encoated aspirin, Prilosec, and Doc-Q-Lace(Colace).
Have the person call their insurance to find out.

You can also look into getting store brand products of Zyrtec. Same amount of active ingredients really.
Walgreens brand, Rite-Aid brand, etc...It may even end up costing less than Xyzal with insurance.
I doubt most insurance will charge less than $20 for 30 tabs of Xyzal (unless the person is on Medicare/medicaid)
Most likely $20-30.
Are you a pharmacist? Right now Xyzal is running a program where you can get $20 off per/prescription up to 5 times.
So that changes it up a bit.
 

Rufus12

Golden Member
Jan 14, 2006
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After using zyrtec with little to no results I decided to try some allegra and it worked perfectly. Only tried it for the first time on monday, but for me it's giving pretty consistent results.
 

imported_Lothar

Diamond Member
Aug 10, 2006
4,559
1
0
Originally posted by: moshquerade
Originally posted by: Lothar
Originally posted by: moshquerade
Originally posted by: Lothar
And FYI, Xyzal 2.5mg is equivalent to Zyrtec 5mg.

30 day supply of Zyrtec 5mg is cheaper than Xyzal 2.5mg where I work at.
The same is true when comparing Zyrtec 10mg with Xyzal 5mg as well.

Yes but Zyrtec is OTC, and Xyzal isn't. So if you have good RX insurance Xyzal could come up cheaper than Zyrtec.

Still no one taking Xyzal here?

Depends...

Some insurance *may* still cover Zyrtec.
The same reason why some insurance still cover encoated aspirin, Prilosec, and Doc-Q-Lace(Colace).
Have the person call their insurance to find out.

You can also look into getting store brand products of Zyrtec. Same amount of active ingredients really.
Walgreens brand, Rite-Aid brand, etc...It may even end up costing less than Xyzal with insurance.
I doubt most insurance will charge less than $20 for 30 tabs of Xyzal (unless the person is on Medicare/medicaid)
Most likely $20-30.
Are you a pharmacist? Right now Xyzal is running a program where you can get $20 off per/prescription up to 5 times.
So that changes it up a bit.

Yes.
Well, if the person has a coupon then they should use it.
 

lightstar

Senior member
Mar 16, 2008
579
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my mom has taken both and they both work the same. zyrtec is way cheaper- OTC. . . .nasal sprays such as nasonex and astelin work well for allergies. . . .singulair would also be an option
 

yhelothar

Lifer
Dec 11, 2002
18,409
39
91
Originally posted by: Darkstar757
I recommend sublingual drops. This is what I am taking to get rid of my allergies.


Darkstar

Wow I never knew they had these.
I had the allergy shots, and the side effects were hellish. it was basically getting a REALLY NASTY bug bite, in which my whole arm would swell up, burn and itch.
But after a year with 1-2 shots a week, I'm cured now.
I don't get allergies anymore.

It was about $400 for the whole thing, but worth it if your allergies are really bad, considering you don't have to deal with them anymore for the rest of your life. These sublingual drops would be a godsend without the side effects.