I use a 3770K overclocked at 4.6 GHZ, and 290X in Crossfire. Crossfire does not work in X-Plane 10 and will probably never work. It's also OpenGL, I'm unsure if Amd's OpenGL implementation is good or bad and if Nvidia's would be any better, but SLI doesn't work either anyway. I also run it on an I7 930 @ 4.0 GHZ with a gtx 680 and it runs worse.
The CPU load is never 100%, with or without Hyperthreading, it's more around 40% on average, and from what I recall not on all cores either. Video card utilization, at least for me, is between 40% and 100% (going up and down every 2-3 seconds), and it is using about 3.6-3.7 GB of video ram with uncompressed textures at 4K resolution.
If I use the cpu at stock speed (3.9 GHZ), and keep video card settings the same, I lose about 7-8 fps, so even though the cpu is not fully loaded, speed seems to make a much bigger difference than cores. It struggles to keep 30 fps with decent graphical settings at 4K (also used triple screen 1080p displays, which was just as bad). This is also with the video card overclocked to 1220 MHZ core and 1550 MHZ ram. Using stock video card settings drops anoter 5-6 fps (1000 MHZ core, 1125 MHZ ram).
Everything maxed out and it literally runs at 1 fps. At 1080p the framerates are obviously better, but cpu utilization is the same, regardless of cpu (I7 930 or 3770K).
My opinion is that cpus and video cards that run as fast as possible give better results than having a million number of cores in the current X-Plane 10 version.