I think it would be possible to have a board that supports both chips. It'd be one big board though, although I doubt you will get them to run simultaneously or in SMP mode. Anyone remember the Apples from the mid 90's that had a x86 chip on an expansion board? You could either boot them into DOS mode and use the 486 chip or boot up into the MacOS and use it like a normal mac. It was incredibly expensive though, because there was 2 sets of memory for each and 2 memory controllers. They were able to use the same storage system though, and I think aside from the memory, everything else in the system was shared. Couldn't see the point in doing this with current AMD/Intel chips as what's the point of having 2 x86 cpus that will essentially do the same thing but can't run at the same time. Maaaybe if you want to be really uber like, you could think about it with the Athlon64 and P4. But then, I really don't think you'll ever get them to operate simultaneously which kinda negates the point of having 2 cpus on one board.