The vid/sound cards don't really matter to the remote. The software does. If your remote emulates a few keystrokes, you might be able to use it to control other applications (PowerDVD, nero Home, zoom), but they'd probably be a lot easier to use with a kb/mouse. If the remote is 100% compatible with Windows Media Center, why not get it anyway? The Media Center app is optimized for TV and remote use anyway, and it's pretty user-friendly.