About 10 years ago I came home, turned on my monitor, and saw a warning from InnocuLan stating that it's holding off Klez from infecting my shared partition. After dismissing that dialog, another one came up stating it was holding off Nimda.
My wife worked from home, using a company-issued laptop, and I asked her if her anti-virus threw up at all: "No". I had her run a quick scan with McAfee...nada. Checked the signatures, they were about a week old (back then, default option for checking for updates was once a week), but the sigs were not as old as Klez or Nimda which had been released a couple months earlier. So we downloaded the L&G sigs, and lo' and behold, McAfee reported she was infected...but immediately suffered epic fail to clean her machine.
So I uninstalled it, installed InnocuLan, and it happily cleaned her machine (took about six hours though, everything was infected). A couple of days later she insisted that I had to re-install McAfee, because it was an IT requirement from her company. They were quite insistent about it.
I told her that since I paid 100% of the broadband cable fees, and that it was my home network and my machines, that her only option with a machine running McAfee was dial-up.
She informed her IT dept. that she wouldn't be using McAfee any longer.
But I digress, I weep for Intel. I just hope they don't do what I think they're going to do...