Overall I thought it very hilarious. The gags and jokes were all well done. My only beef with it:
****** POTENTIAL MINOR SPOILER ********
In traditional Hollywood style they had to incorporate a love story. Toward the end of the movie, the jokes and comedic hijinks took a back seat to this sappy love story. I dont' mind love stories one bit, but it was overdone in Van Wilder.
Love story or not, the movie made me laugh and had plent of gorgeous women. Thumb's up from me.