I can only give my perspective on the asus one since that's what I own and I've never seen the alienware in person. The picture is sharp, colors seem to pop, and 120hz is great. 3d is awesome but it's either you love it or hate it and I love it. From what I've read the alienware has a super nice stand and looks awesome. The asus stand is pretty basic. I don't believe there is much separating picture quality. I do believe the asus has a brighter picture and that really comes into play when using 3d since the shutter glasses really reduce brightness. I'm happy with the asus.