Hood River is nice but it's a ways east. If/when my wife and I move back I'd like to look @ Hood River. Portland is only about an hour away so it's not too bad.
Vancouver is a lot better than it once was. It used to be kind of disgusting and run down but there has been a lot of renovation and improvements to the downtown area and it's actually not that bad of a place to live now. It's right across the river from Portland, and for all intents and purposes it's just a less-cool extension of the PDX metropolitan area. While staying with a friend one night in 1996, I had all my worldly possessions stolen out of my car while moving, so I've still got a little bit of a beef with The Couv.
The weather in SW Washington and NW Oregon is beautiful in the summer, which as I recall last year was on a Tuesday. In all seriousness I would suggest being fully prepared for a lot of rain if you move there. Until last year, I'd lived my entire life in Portland/Salem/Seattle and the surrounding area, and while I'm used to the rain, I know it gets to a lot of folks. The last couple years have been exceptionally bad, with 2010 seeing rain or some form of precipitation for ~ 90 days straight at one point.
I want to move back, but career and money wise Vegas is the place for my wife and I right now.