If money is no object, then go with Adaptec. If you are looking to save some money, try Tekram or Advansys (which I think has a new name, I/O something-or-rather). Tekram cards, by all accounts I've read, are excellent and well supported at a fraction of the cost of the name brand Adaptec. I have an Advansys card in my system (only SCSI-2) that's been working fantastically for about two years without so much as a hiccup of protest, ever. I only run optical drives off of it right now, but I have a 9GB SCSI drive sitting behind me that's going to be installed shortly.