The largest endothermic chemical reactions on earth may occur in comet impacts where H2O ice reacts with various carbon bearing ices such as CO, CO2, ethane and methane to create longer hydrocarbon chains. I suggest that "abiotic oil" from comet impacts is the origin of the planet's petroleum reserves. In the West we consider petroleum to be a "fossil fuel," but the Russians have long regarded oil to result from abiotic origins.
The endothermic chemical reactions in comet impacts may also have the effect of clamping the impact shock-wave pressure below the melting point of rock with the effect of preserving the differentiated comet core that resulted from the heating of short-lived isotopes of the early solar system. And the lack of pseudotachylite melt rock in comet impacts may mask comet impact craters from recognition by geologists.
A similar endothermic chemical reaction may occur in the atmospheric testing of nuclear weapons leading to the well known "double flash" phenomenon. The secondary flash is likely the result of the burning of the endothermic chemicals created in the primary shock wave, perhaps primarily: xO2 + N2 <> 2NOx
A secondary burn from a pair of comet impacts on the Hudson Bay and upper Lake Michigan from the Younger Dryas impact event (12,900 ya) may have tossed large chunks of the Laurentide ice sheet along the Atlantic Coast, creating the Carolina Bays.