What is the difference between gaming and professional GPUs? Binning and drivers.
Binning: Professional cards usually get the top bins, meaning they are likely to have better perf/watt than consumer cards.
Drivers: This is the most important one. The drivers for professional cards are certified, which is important for certain applications such as SolidWorks. They are also designed for accuracy rather than raw speed, so they don't take some of the quick-and-dirty shortcuts that gaming drivers do. In the case of Nvidia, some compute-related features are also intentionally gimped on consumer cards, so if you want them to run at full speed, you'll have to get a Quadro.