Seizures and convulsions, dizziness, tremors, migraines and severe headaches (triggered or caused by chronic intake), memory loss (common toxicity effect), slurring of speech, confusion, numbness or tingling of extremities, chronic fatigue, depression, insomnia, irritability, panic attacks (common aspartame toxicity reaction), marked personality changes, phobias, rapid heart beat (tachycardia - another frequent reaction), asthma, chest pains, hypertension (high blood pressure), nausea or vomiting, diarrhea, abdominal pain, swallowing pain, itching, hives / urticaria, other allergic reactions, blood sugar control problems (e.g. hypoglycemia or hyperglycemia), menstrual cramps and other menstrual problems or changes, impotency and sexual problems, food cravings, weight gain, hair loss / baldness or thinning of hair, burning urination & other urination problems, excessive thirst or excessive hunger, bloating, edema (fluid retention), infection susceptibility, joint pain, brain cancer (in pre-approval studies on animals), death.