18 inches is nothing as others have stated.
The D5 is raited at 3.5m for head pressure, which translates to ~11ft.
Also head pressure isn't as important as flow. Sure there is a relationship between the two, but 18 inches wont impact it very much, unless were talking about 18 inches using 1/8ID tubing, then your going to have flow problems, which is a lot greater then head pressure issues.