Here are some guidelines:
at 240 MHz FSB (HTT) and RAM frequency set to 166MHz your ACTUAL RAM frequency is 200 MHz, so set latencies whatever you would for 200 MHz
at 266 MHz FSB (HTT) and RAM frequency set to 150MHz your ACTUAL RAM frequency is 200 MHz, so set latencies whatever you would for 200 MHz
at 300 MHz FSB (HTT) and RAM frequency set to 133MHz your ACTUAL RAM frequency is 200 MHz, so set latencies whatever you would for 200 MHz
To ensure your RAM is fine, use the next LOWEST RAM setting (like at 245 HTT, set the BIOS to 150MHz RAM)
To start with just set HT frequency to 600, setting it to 600 REALLY means that you are setting it to 3x whatever the FSB (HTT) is. This will keep it below 1000 MHz and stable. HT frequency is one of the least important factors, so don't worry about it for now. If you're stable, then try 4x later if you like, but it is really a fraction of a percentage type difference in overall application speed, not worth worrying about.
It is not as simple as AXPs, but overall the A64 solution is a good deal more flexible. You can TOTALLY isolate RAM and CPU with the use of RAM dividers, which allows you to verify each component of your system 100% independent of the others. This is something not possible on current Intel or AXP platforms.
I would be incredibly surprised if you can't run 2.2 GHz at default voltage because of the CPU. Keep tweaking your settings. Start with 2160 (240x9 / 166MHz RAM setting in BIOS) because that will keep your RAM at 200 MHz.
I would start with the default RAM timings for now, you can tweak the RAM stuff later. Honestly if you're playing games, 2160 MHz is plenty to reach a video card limit in most games.