If you get a USB 3.0 enclosure, and a new 7200 RPM drive, you should get 95%+ native speeds, barring a bad cable, or controller compatibility (Z68 has no USB 3.0 support, so that means nothing). 150-250MB/s should be possible, depending on host controller, bridge, and how well they play with each other.
If you buy a penny-pinching prebuilt, expect the slowest model HDD they could make, and don't get excited about the bridge chip, either.