Yeah, I have an eSATA combo port on my new laptop, so there is nothing else to install in regards to expansion cards. The only difference in USB and eSATA for me is that I need 2 cables (power from a free USB port ironically enough, and data) for eSATA on my laptop. The hot plug feature seems to work just fine for me though, so in that respect there is no advantage to using USB. I bought a 0.5M eSATA cable from Monoprice to keep the cabling tidy too. I don't think saving carrying a cable around is enough to warrant buying an Express card or a new laptop.
If I'm on the go, I can clone to the eSATA drive, but at home I just clone over GbE to a network share. GbE gets around 40MB/sec sustained transfer, which is fine since my laptop drive is only 37GB of data. USB 2.0 cloning does seem painfully slow in comparison though, even though theoretically it should be able to do that kind of speed.