Northbridge(IOH) is also involved in uncore. Look in CPU-Z it shows the Uncore frequency as the Northbridge frequency. Once you get over about 3.2 the IOH core voltage needs to be adjusted upward. With 2000 memory frequency(4000 uncore) a lot of people I have seen need to raise IOH up to at least 1.24v from 1.1v default. QPI needs to be raised also but that is because the QPI link is higher than default- 7200+ usually- 8000 is the general limit and many chips can't go that far. QPI is also for the IMC and the voltage will need to be raised the more memory you have/tighter timings. My CPU has a weak QPI and can't go over about 7200 even if I raise QPI to 1.5v+. If you have a 965/975 the BCLK can be much lower, and IOH and QPI, since the multi can be raised instead. That is the only reason to buy those chips other than bragging rights/e-peen/non-OC'er.
And for the OP's question I believe it only shows a benefit in synthetic benchmarks and it might lower superPI time. The i7 needs 6+ cores to benefit much from triple channel memory according to Intel so there won't be much benefit in everyday apps.