If so, the only way to get sound off your subwoofer is if it has speaker level inputs. You will have to wire it like this:
-From audigy2 to QSC amp
-from QSC amp to speaker level inputs of subwoofer
-from subwoofer speaker outs to main speakers.
No you don't, I have a Velodyne Sub, with line-level input which his subwoofer has (he provided a link above). So long as he sets it up as I described above it will work. The Audigy will act as a preamp and perform bass management functions as long as you have it set up properly.