I bought a set of Klipsch Promedia 2.1's about a year ago and was sorely disappointed. Admittedly a big part of it was the fact that I live in an apartment and the devastating bass was bothering the neighbors (even at moderate volumes), but even the sound quality was just not up to expectations.
The main problem was the harshness of the horn tweeters. I'm not an expert on speaker technologies, but from what I have heard horns are a rather outdated technology compared to "real" tweeters. Either way, the satellites can be downright painful even at moderate volumes.
So they weren't a good fit as PC speakers, but I figured why not hook them up to my PS2 (using a phono-to-RCA adapter) and use them for DVD's and PS2 games? Again they were just not satisfactory. When playing DVD movies, dialogue was WAY too quiet compared to everything else due to the poor midrange reproduction. To even understand the dialogue, I had to increase the volume to the point where sound effects were practically ear-shattering. Again, the balance just was not there.
Anyway, they ended up finally finding a home... in my car. I put the sub in the trunk and ran the wires to the sats in the backseat of my hatchback (240SX). Then I used my portable CD-player and a DC-to-AC transformer to power them. Of course, again the harshness almost became their undoing again... Until I covered them up with a cloth to "filter out" the highs, and FINALLY I found a place where they can be put to use.