I popped it in and it saw it immediately...just needed to make sure I was using a recognized dual core bios for the mobo and no problem...later on I had to install the X2 drivers to correct an issue with a game, but that can be added at anytime without reinstallation...
If you do have several issues in games when other are not I would recommend doing a fresh install, with latest official chipset and video drivers, along with X2 drivers....