There really is no such thing as too cool, though there are certain situations where getting a proc too cold has caused certain processors to get odd errors or even freeze up(literally?) but, I really haven't seen any issues going as low as -50C, errors start to come up with multiple phase change units which guys have run as low as about -170C with tripple systems. I'm actually working on a chilled liquid system that will run alcohol, I'm currently aiming for 0C load. That should get me in the area of 3.2-3.3ghz, make my A64 last me a couple months longer. Then it'll get it's really workout on a 9450 around christmas, maybe something special on black friday.