Study: Too Much Marijuana Makes Pain Worse, Not Better

[IGBT]

Wallace and colleagues call for further research, including studies of the clinical value of the pain-reducing effects. Based on this studies findings, Wallace said he would not recommend marijuana as a method of pain reduction at this time.













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[potato28]

Makes you very fat quickly too

 

[Ns1]

My GF, who has racked up over 2m worth of medical expenses in 17 years, would beg to differ.

And what the fuck, chile's in skin? Why don't they get a sample 100 people with cancer, fibro, whatever, give 50 of them MJ and 50 of the placebos (hell even prescription drugs) and see which one's more effective

 

[spidey07]

Oh boy, what an entire bogus study.

How about a contrast with other analgesics and dosage?

 

[loup garou]

This just in, too much prescription pain killers makes you dead, not better.

 

[waggy]

Originally posted by: NeuroSynapsis
My GF, who has racked up over 2m worth of medical expenses in 17 years, would beg to differ.

And what the fuck, chile's in skin? Why don't they get a sample 100 people with cancer, fibro, whatever, give 50 of them MJ and 50 of the placebos (hell even prescription drugs) and see which one's more effective

yeap.


and that "study" was bullshit. 15 healhty people with pain induced. why don't they take people in real pain.

like neuro said take people with cancer, fibro etc. then do it.



when i have pain specialist hinting that i should smoke moderate amounts of pot (2 pain clinics have hinted at it) i start to think something is there.

 

[kush23]

give the test patients some kush and see if they still got any pain...

 

[nageov3t]

too much of anything is bad, shouldn't they be studying what happens when you take exactly enough?

 

[imported_bum]

Did anyone actually thinking marijuana worked as a general pain killer in the first place? This is almost as dumb as the study that recently claimed "high doses" of marijuana could cause depression after observing rats that were injected with THC.

 

[waggy]

Originally posted by: bum
Did anyone actually thinking marijuana worked as a general pain killer in the first place? This is almost as dumb as the study that recently claimed "high doses" of marijuana could cause depression after observing rats that were injected with THC.

actually it has been proven tha tit does work for those with chronic pain.

 

[yllus]

Originally posted by: bum
Did anyone actually thinking marijuana worked as a general pain killer in the first place? This is almost as dumb as the study that recently claimed "high doses" of marijuana could cause depression after observing rats that were injected with THC.

Oh, thanks doc. I'll go tell my friend who has cancer that her medically prescribed marijuana doesn't actually work. I bet she'll be really surprised!

 

[Tiamat]

Wow, talk about a waste of a study. A sample size of 15? That's nowhere even close to being statistical.

 

[Old Hippie]

when i have pain specialist hinting that i should smoke moderate amounts of pot (2 pain clinics have hinted at it) i start to think something is there.

I can say for a fact, it potentiates opioid painkillers.

 

[rivan]

Originally posted by: NeuroSynapsis
My GF, who has racked up over 2m worth of medical expenses in 17 years, would beg to differ.

And what the fuck, chile's in skin? Why don't they get a sample 100 people with cancer, fibro, whatever, give 50 of them MJ and 50 of the placebos (hell even prescription drugs) and see which one's more effective

Because it's consistent, and reproducible. People with cancer, fibro, and whatever, don't feel the same from day to day. They have ongoing treatments that may influence their pain level, and would thus skew the results.

I'm not going to agree or disagree with the study without reading it - but that's why you choose a methodology of study - to remove as many variable elements from the conclusions as they can.

 

[torpid]

Originally posted by: waggy

Originally posted by: bum
Did anyone actually thinking marijuana worked as a general pain killer in the first place? This is almost as dumb as the study that recently claimed "high doses" of marijuana could cause depression after observing rats that were injected with THC.

actually it has been proven tha tit does work for those with chronic pain.

Not the same thing as working as a general pain killer IMO.

 

[FoBoT]

just go straight to heroin

 

[Anubis]

Originally posted by: loup garou
This just in, too much prescription pain killers makes you dead, not better.

i loled

 

[meltdown75]

Aren't there are other positive effects besides pain releif? Obviously stress levels would be reduced, and it helps with stomach ailments and nausea too. I didn't think anyone used marijuana strictly for pain. Would they still be able to get / use traditional meds in addition to the weed?

I caught a documentary a while back on Dishnet... one woman that suffered from MS her entire life could barely speak because she had such a horrible stutter. When she smoked a bowl, she was able to talk and not just say "far out" or whatever. The before and after was incredible.

I'm pretty cynical when it comes to the notion that most studies on pot prove what they are paid to prove. Too many agendas out there to take any marijuana study seriously.

 

[Leros]

I have a friend who has had chronic back pain her entire life. She's done therapy, taken all sorts of pills, gone to a chiropractor and nothing has worked. In college she tried weed and said for about a week afterwards the pain goes away completely. She now smokes it regularly (weekly or so) to stop the pain.

 

[Anubis]

Originally posted by: meltdown75
Aren't there are other positive effects besides pain releif? Obviously stress levels would be reduced, and it helps with stomach ailments and nausea too. I didn't think anyone used marijuana strictly for pain. Would they still be able to get / use traditional meds in addition to the weed?

I caught a documentary a while back on Dishnet... one woman that suffered from MS her entire life could barely speak because she had such a horrible stutter. When she smoked a bowl, she was able to talk and not just say "far out" or whatever. The before and after was incredible.

I'm pretty cynical when it comes to the notion that most studies on pot prove what they are paid to prove. Too many agendas out there to take any marijuana study seriously.

yes and it does wounders for people who dont have an apetite dude to things like kemo,

and all drugs dont work the same for every person, TCH is no different

 

[sdifox]

Originally posted by: Tiamat
Wow, talk about a waste of a study. A sample size of 15? That's nowhere even close to being statistical.

Maybe it was a typo. They were going to type satirical and not statistical. Could happen.

 

[Miramonti]

FoxNews butchered the actual study results, which show cannabis can have a significant impact reducing pain. :roll:

Newswise ? Although smoking "moderate" doses of cannabis helps reduce pain in healthy research volunteers, pain is actually increased at high doses.

The November issue of the journal Anesthesiology features a study showing that marijuana, or cannabis, reduces pain only within a narrow dose range. "Our study suggests that there is a therapeutic window for analgesia, with low doses being ineffective, medium doses resulting in pain relief, and high doses increasing pain," comments lead author Dr. Mark S. Wallace of University of California, San Diego.

Dr. Wallace and colleagues evaluated the effects of smoking cannabis on pain responses in 15 healthy volunteers. On different days, the research subjects smoked low, medium, or high doses of cannabis (based on the content of 9-delta-tetrahydrocannabinol [THC], the main active chemical in cannabis), or an inactive placebo. Pain was induced by injecting capsaicin, the "hot" chemical found in chili peppers, into the skin. Capsaicin injection is a standard technique used in pain studies.

Five minutes after smoking, none of the three doses of cannabis had any effect on pain responses to capsaicin. However, 45 minutes after smoking the moderate dose of cannabis, pain was significantly reduced?approximately six points lower on a 100-point scale, compared with the inactive placebo.

In contrast, 45 minutes after smoking the high dose of cannabis, pain scores were increased?about eight points higher than with placebo.

The low dose of cannabis had no effect on pain scores. None of the three doses affected the extent of secondary hyperalgesia?that is, the spread of pain beyond the area injected with capsaicin.

Levels of THC measured in the blood were significantly related to reduced pain scores at the moderate dose of cannabis, but not to the increase in pain with high-dose cannabis. The volunteers' sense of feeling "high" increased with each dose of cannabis, even though the pain-relieving effects did not.

Research has suggested that the active components of cannabis might have pain-reducing effects, but few studies have actually looked at how cannabis affects pain in humans. "With several states having passed laws legalizing the medical use of cannabis, there has been a call for more research on medicinal cannabis," says Dr. Wallace. "The Center for Medicinal Cannabis Research received a large grant from the State of California to investigate the medicinal use of cannabis, and this is one of the many studies that were funded through the Center. The research arising from the Center can provide an evidence basis for deciding the appropriate use of cannabis and related compounds as medicines."

The results are an important addition to research on the pain-relieving potential of cannabis. "This is the first study using different doses of cannabis and a tightly controlled pain stimulus that suggests that cannabis has a therapeutic window of pain relief," adds Dr. Wallace. Although the researchers were surprised at the delayed analgesic effect of cannabis, the increase in pain with high-dose cannabis is consistent with earlier studies.

Dr. Wallace and colleagues call for further research, including studies of the clinical value of the pain-reducing effects. Pending more information on this and other issues, including the potential for abuse and safety issues of inhaled cannabis, the researchers conclude, "We cannot recommend advocate a place for using cannabis in the treatment armamentarium at this time."

 

[Skacer]

Dr. Wallace says everyone should stop smoking pot and take "Dr. Wallace's Pain-B-Gon" medication today, may cause bleeding, ulcers, death, mild schizophrenia, major schizophrenia, anti-gravity, or anal leakage.