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Study Points to Genetic Predisposition for Lung Cancer

IGBT

Lifer
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Tobacco Smoke Is the Trigger

The study points to the existence of genetic factors that contribute to the disease, even after taking the familiality of smoking into account, suggesting that lung cancer can be viewed as a disease in which a single environmental factor, tobacco smoke, can turn a genetic predisposition into disease. The study, entitled "Familial risk of lung carcinoma in the Icelandic population," appears in the December 22nd edition of JAMA and in the online edition of the journal.


Genes Play Larger Role in Early Onset Forms of Lung Cancer

This increased risk is particularly notable in relatives of patients diagnosed with the disease before the age of 60, suggesting that the genetic factors play a larger role in early-onset forms of the disease. Spouses of patients are also shown to be at a significantly increased risk of developing the disease, underscoring the very powerful role of environmental and behavioral factors, most notably smoking.
 
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