BEIJING, Jan. 4 (Xinhuanet) -- Monkey experiments have shown that embryonic cells transplanted into the brain can reverse the debilitating effects of Parkinson's disease, Japanese researchers reported on Monday.
The study, published in the Journal of Clinical Investigation, supports arguments that stem cells taken from days-old embryos can be used to replace damaged tissues in a range of diseases, experts said.
In the study, Takahashi and colleagues at Kyoto University generated neurons from monkey embryonic stem cells and exposed them to a growth factor called FGF20, which is produced exclusively in the part of the brain affected by Parkinson's disease.
The growth factor increased the development of dopamine-producing neurons, which the researchers then transplanted into monkeys with a primate model of Parkinson's disease. They found that the transplanted cells functioned as dopamine-producing neurons and lessened Parkinson's symptoms.
Parkinson's is caused when key brain cells that produce the message-carrying chemical dopamine die off. Symptoms start with a trembling and patients can end up paralyzed. There is no cure.
Proponents of embryonic stem-cell research believe their field offers a good opportunity, while the opponents say using a human embryo for such research or even treatment is unethical.
J. William Langston of the Parkinson's Institute in Sunnyvale, California calls the study a milestone, however he causions that the reported number of surviving dopamine-producing neurons was very low at 1% to 3%, which is far below the approximately 10% estimated to survive for fetal cell transplants.
To be useful in humans, Langston says, it may be necessary for more dopamine-producing neurons to survive and for the survival to be long-lasting. Enditem
(Agencies)
Good news to hear! Hopefully we can have the same stories coming from the US with research in California being supported.
 
				
		 
			 
 
		 
 
		 
 
		 
 
		 
 
		 
 
		 
 
		 
 
		 
 
		 
 
		
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