From DC, I would reccomend you tkae 81 South to 40W. Then you can visit the lovely state of Tennessee.
You will start out in the mountains where you can pick up some good moonshine. Then you can stop off at Dolly Wood in Pigeon Forge. Then its off to Nasvhille. Believe me though there is so much to do between Dollywood and Nashville. You have the Hank Williams Jr. museum, Loretta Lynns's museum, I could go on and on. You just have to pay attention to the billboards.
Lets see, in Nashville you can visit the Country music hall of fame. And we also have the "worlds biggest adult bookstore." Don't know if its true or not, but thats what the sign says.
Then you can head down to Memphis and see all the old people crying at Graceland and you can see the grave of Elvis.
Phew thats it in a nutshell. You could dip into Alabama, but Skoorb was not kidding when he said watch your ass down there.