One caveat - I'd only upgrade one at a time, then let it run. Whenever you're making changes to a network, ALWAYS only change one thing at once. If you do both at once, who knows where the problem is - The Supervisor, the MFSC or something between them?
I'd start with the Supervisor module, then update the MFSC a week or so later, unless you're in a big hurry.
- G