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Hard to say.. many vitamins dissolve in water and leave when you pee, but I believe there is something to taking more than just the RDA 100% of vitamins.
Be carful though, you can OD on vitamins that store up in your fat, including A and D...
Don't megadose in one vitamin, but iirc, when I took Amway's DoubleX I felt much better and energetic and it definitely wasn't a placebo effect. Since it's a great combination of different nutrients, not just a megadose of one, I think it helped
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