Well theres not really anything specific you need for WS.
One thing to check for on any LCD is dead/stuck pixels. Download Dead Pixel Buddy and see if you can spot anything.
Other than that, the best software for WS monitors is running WS games. Try out some Source-engine games or proper WS racing games. It just feels more immersive when properly done.
I also placed my windows around different (well for any programs that save the window size/position). Like I keep my FF window full height, about 75% width, so it leaves the right quarter of the screen for Winamp and ICQ and other small stuff. No need to run your web browser full screen unless you have one of the extensions that allows you to side-by-side tabs/webpages.