An ex-gf's time of the month is apparently ridiculously painful. She goes nuts on the NSAIDs (4x dose) then, just as an example. Not saying I agree with it, but that's how it is.
I avoid them unless I absolutely have to for muscular pain. Last time I think I took any was after a day-long mountain hike with most of my body feeling like one giant knot. Never exceeded dosage, too much pharma and medical knowledge in the family to go for that.
800mg ibuprofen (or about 600mg naproxen) is how much they give in a single maximum prescription strength pill. And generally the prescriptions state "take one every 8 hours, with meal, etc etc" generally until either the pain is gone or until the prescription is out... and they'd prefer you to not finish that bottle but is acceptable if the pain is terrible (and generally they'd want to give you some opiod-related pharm if the issue is at that level).
True NSAIDs aren't exactly life-threatening at maximum prescription dosages for the long-haul. I never suffered complications when I got into a rhythm with the shit. But the real concern, and very possible at those excessive dosages for
long-term cases, is stomach ulcers. Treatable, and not likely (but complications are always possible) to prove fatal, but not something you'd probably want to go through if you could avoid (this is the motivation I use to ween myself from the dependencies).
I'm more worried about my excessive caffeine intake and seriously need to cut back. I'm dreading the first few days and keep procrastinating that recovery. :|