Ok this just recently started happening. I have a 250gb storage drive in my computer. I use it for downloading files onto. My downloads folder on the drive is about 50gb as of right now. Whenever I try to access the downloads folder the explorer shell gets so slow that it seems frozen. All my other programs run fine and I ctrl-alt-del and nothing is using up processing power. It is only that one folder. Any other folder on the drive works fine. The shell isn't completely frozen. I can click on the start menu or try scrolling but it takes about 10 seconds before it does anything. I checked disk defragmenter, and it says there is only 13 percent file fragmentation, so it's not that. When I boot up in safe mode I can access it fine by the way. Anyone have a suggestion?