Cost difference == massive.
If you get 10K rpm drives (more likely than not Ultra-160) you'll be paying a heck of a lot more. You can usually get 2-3 very nice IDE-drives for one "top" SCSI-drives.
The last IBM U160 10K rpm drives I bought (*think* they were 18 GB's, but may have been 36 GBs) were around 400-500 £ if I recall correctly.
In essence, SCSI is not financially viable, unless you're intending to do either of the following two:
* Use a SERIOUS workstation
* Build a server.
SCSI *is* faster, more reliable & Hot-swappable (if you have SCA drives & a hotswap-backplane). There's quite a few benefits for SCSI for SERIOUS systems. I doubt most "home-users" require it.
It depends on what you want to do, really.
I am 99% positive that pretty much whatever you want to do (unless you need real RAID or hotswap redundancy), you will be better off with IDE price-wise. If you've got the cash, go ahead & buy a nice SCSI/RAID-controller & those drives.
However, IDE will be a LOT cheaper. What's your reason behind thinking you might need SCSI? Basically - it boils down to this: Tell us what you want to use the system for & then you'll see whether it's financially viable to use SCSI for it or not. Do be prepared for quite a financial "loss" if you go SCSI... 😀
It's a nice technology, but rather pricy 🙁.
Hope this helps... 🙂