Hah, I was looking for another X299 power forum, and came across you post, and figured I should make it go around, so I'm answering yours (I actually help on other forums, but didn't have an Anantech forum account until now). ;-]
Anyway, you can do this by Opening "Device Manager", going to "Mice and other Devices" (sometimes it can be "hidden under HID devices, depending on the driver writer), and right-click->Properties (or double click the device, either works).
From there, Go to the "Power Management" Tab, and choose "Allow This Device to Wake the Computer". Then click OK (not Cancel, obviously), and it should work.
On some BIOSes, you may have to disable USB Selective Suspend, but I don't, on my ASUS X299, for example.
You probably won't be able to wake it with movement though, or at least not with most mice, it typically requires a button click, given that that switch is a "hard contact" one, and doesn't require constant LED power. S3 has minimal draw requirements, both by-system and per-device, and they're pretty strict, so most LED mice would quickly break the requirement.
I pretty sure there are some mice that have additional motion-sensors and would detect-switch with those (again hard-contact switch), but I'm pretty sure these are in the minority (I've done a lot of device spec work, and don't recall encountering one, but I've been on a hiatus for a bit).
Anyway, hope this helps, probably not the "move to wake" you wanted exactly, but wake with the mouse anyway...
Edit: apologies to the admin, I didn't mean to necro-post, I had reached this page searching on a specific X299 MB h/w issue, and was using the "+2017" syntax to make sure I was getting (mostly) current stuff.
Apparently this picked up on the "related" threads here, which had a 2017 in the title.
My answer isn't irrelevant (still), although the exact text and such would differ for 2002, the concepts/steps are still essentially current.
Facebook
Twitter