Rosetta@Home and AIDS Vaccine Development

Crazee

Elite Member
Nov 20, 2001
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Our Gates foundation grant to develop HIV vaccines started earlier this week (Aug 1), and it has been an exciting time as we are finally able to pursue this goal actively rather than just thinking about it! We have already ordered reagents to put together the first five designs, and there are many more in the pipeline. After this first round of designs is complete, and the designs are close to being sent to our collaborators to be tested as possible vaccines, a high priority will be to extend rosetta@home to design calculations (which shouldn't be difficult, as the same underlying rosetta source code is used) so that all of you can contribute to the second round of designs.

This morning I had to wake up early to go to a BBC radio interview which I think several of you participated in as well. The more media attention, the better for the project, but I'm really not very good at this kind of thing...

Meanwhile, CASP7 has only a few days more to go and we are waiting for the solved structures to be released so we can see how well we did. so far only a few novel structures have been released, our predictions for these are good, but not at atomic resolution, probably because the proteins are longer than those in our pre CASP tests and the search problem is correspondingly more difficult.

Sounds like we should be working on these designs soon :)
 

Smoke

Distributed Computing Elite Member
Jan 3, 2001
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Thanks for the news, Crazee. We are not a massive TeAm but we seem to really be accomplishing good things. :wine:

Dr. Baker is definitely a good leader. :thumbsup: