be aware that technically stripping any DRM protected disks is illegal, because you're circumventing the DRM. Secondly on some games a perfectly ripped ISO wont work because the DRM wont let it, and even worse, some games' DRM wont let a game run just because you have installed game iso rippers or virtual CD drives.
Dont take this as a whine directed at you, i find the whole situation totally retarded. You buy the damn thing and get lumbered with this crap, while the pirates just remove it. (yes yes there is and certainly has been plenty arguments about who's fault this is and wether or not the companies are right to do this, I'm just saying it's a bloody nuisance regardless)