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random thought re psoriasis

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tommo123

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the cells divide much more quickly right? does this mean you get a version of accelerated healing as far as the skin is concerned?
 
NO. I have psoriasis and if that was the case I'd be willing to bet everyone would want it.
 
how does that work? the cells divide more quickly but you don't heal that part of the skin any more quickly?
 
tommo123 said:
how does that work? the cells divide more quickly but you don't heal that part of the skin any more quickly?
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The wound healing process causes increased cell division rates in a normal person. This increased rate is probably close to the maximum possible rate in some cases, so a person with psoriasis might have no advantage of simple division rate where it counts. (There's a maximum speed at which cells can divide. The genome can only be replicated at a certain rate for instance. Ignoring some odd things that can occur).

Furthermore, the increased division in psoriasis isn't necessarily the right kind of division, i.e. it might not be directed at healing and repairing the wound. Think of a bricklayer that's very fast, but doesn't care where he lays the bricks - that isn't the guy you want repairing a wall.
 
good visual. thanks 🙂

could psoriasis then - in theory - be manipulated to help with healing? if you could understand it, take control of it? make the bricklayer be more precise in his work?
 
Maybe

Things like psoriasis and eczemas have different causal agent/mechanisms ranging from chemical damage to being an autoimmune reaction to just being simply unknown.

Possibly in the future, given sufficient advancements in gene modification and therapy, what you have said might be realizable.
 
cool. i have it at times and take some steroid creams which apparently kicks my immune system in the nuts for a time
 
A normal steroid cream shouldn't affect your immune system like that. You're probably taking something like Halobetasol propionate, which can affect your skin as it's a strong steroid. Your immunal response might stem from the psoriasis but the cream shouldn't be exacerbating it. The only drug off the top of my head that's been used for psoriasis use that can affect your immune system (and kidneys too) is methotrexate. It's a cancer drug that was found to be very effective for psoriasis. It's pretty potent though and you won't usually take it unless your condition reaches above a certain percentage of your body and even then you won't take it for very long, maybe 6 months. I took it and it's not fun, trust me. While I'm not a doctor from what I've been told psoriasis is more akin to the way cancer works. It also can lead to psoriatic arthritis, which is very painful. I keep mine under control fairly well.

Anyway if there could be anything gained from the way psoriasis works to help the healing process I'm sure they've already explored it but for all we know about it psoriasis is still a pretty big mystery and we're really no closer to a cure than we were when I had my first outbreak at 2 years old (I'm 34 now).
 
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pw38 said:
A normal steroid cream shouldn't affect your immune system like that. You're probably taking something like Halobetasol propionate, which can affect your skin as it's a strong steroid. Your immunal response might stem from the psoriasis but the cream shouldn't be exacerbating it. The only drug off the top of my head that's been used for psoriasis use that can affect your immune system (and kidneys too) is methotrexate. It's a cancer drug that was found to be very effective for psoriasis. It's pretty potent though and you won't usually take it unless your condition reaches above a certain percentage of your body and even then you won't take it for very long, maybe 6 months. I took it and it's not fun, trust me. While I'm not a doctor from what I've been told psoriasis is more akin to the way cancer works. It also can lead to psoriatic arthritis, which is very painful. I keep mine under control fairly well.

Anyway if there could be anything gained from the way psoriasis works to help the healing process I'm sure they've already explored it but for all we know about it psoriasis is still a pretty big mystery and we're really no closer to a cure than we were when I had my first outbreak at 2 years old (I'm 34 now).
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?

Corticosteroids are used for psoriasis all the time. They are strong immune suppressants.
 
Gibsons said:
?

Corticosteroids are used for psoriasis all the time. They are strong immune suppressants.
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Depends on the class used and the severity of the skin condition. You are correct though they do have immunosuppresive qualities. I didn't mean to make it sound like they don't. From my experience though the affects on the immune system aren't that far reaching but of course every situation is different.
 
The dead sea has been known to bring about psoriasis remission. It is unclear as to whether it is the salts or decreased uv light (remarkably the air is densest there because it is so low below sea level). Anti inflammatory and anti mitotic treatments feed the medical industrial complex so that's what's researched,sold, and pushed. Whether empirical solutions (?anti uv cream, honey, dead sea salt?) are effective is anyone's guess.
 
uv light is a known treatment but some people take home salts and have baths apparently - and that helps (again, apparently).
 
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