cant find it now but i have also seen where somebody sent there double sided 2400 ram kit of for rma and got back a single sided kit which performed below there old ram when set at 1866mhzThe highly clocked MFR-based kits are not slower because of the memory timings, but mainly because they are single sided.
As you can see, a DDR3-2933C11 MFR memory kit is slower than a DDR3-2400C11(!) kit. That is nothing short of sad.
If I remember correctly from my AMD days, at the same frequency, a dual rank DIMM may be able to achieve higher throughput due to interleaving.
But, single rank should in theory support a higher frequency so there is some trade-off there.